Dard S, Ulmann A, Lacombe M, Grünfeld J P, Michel J R
Nouv Presse Med. 1981 May 23;10(23):1909-11.
During aetiological investigation of recently developed hypertension in a 31-year-old man, isolated dissection of the upper branch of the right renal artery was discovered. Injection, after sodium depletion, of saralasin, a competitive angiotensin II inhibitor, resulted in significant fall of the mean arterial pressure. During sodium depletion, the plasma renin activity was higher in the right renal artery (17.8 ng/ml/h) than in the left artery (9.4 ng/ml/h) and the infra-renal portion of the inferior vena cava (8.7 ng/ml/h). These figures suggested that surgical treatment of the dissection would have beneficial effects on blood pressure. Six months after resection of the pathological arterial segment and replacement by a graft from the internal saphenous vein, blood pressure had spontaneously returned to normal levels.
在对一名31岁男性近期发生的高血压进行病因调查时，发现右肾动脉上支孤立性夹层。在钠缺失后注射竞争性血管紧张素II抑制剂沙拉新，导致平均动脉压显著下降。在钠缺失期间，右肾动脉的血浆肾素活性（17.8 ng/ml/h）高于左肾动脉（9.4 ng/ml/h）和下腔静脉肾下段（8.7 ng/ml/h）。这些数据表明，夹层的手术治疗对血压可能有有益影响。切除病变动脉段并用大隐静脉移植物置换6个月后，血压已自发恢复至正常水平。
