Sullivan J L, Herrod H G, Levine L
Am J Dis Child. 1981 Jul;135(7):618-20.
The evaluation of suspected humoral immunodeficiency includes quantitative immunoglobulin levels and specific antibody assays. The Schick test is a simple procedure for measurement of specific diphtheria antibodies that has been overlooked because the availability of Schick test materials has been limited in recent years. We assessed the efficacy of the Schick test in screening for antibody deficiency states in 23 children. Five had positive Schick test reactions. All five had clinical and immunologic findings consistent with a primary immunodeficiency disorder. Each of these patients had at least one other abnormality of antibody formation detected. The Schick test is a simple screening device helpful in the assessment of immunocompetence.
对疑似体液免疫缺陷的评估包括定量免疫球蛋白水平和特异性抗体检测。锡克试验是一种用于测量特异性白喉抗体的简单方法，但近年来由于锡克试验材料的供应有限而被忽视。我们评估了锡克试验在筛查23名儿童抗体缺乏状态方面的效果。5名儿童锡克试验反应呈阳性。这5名儿童的临床和免疫学表现均与原发性免疫缺陷病相符。这些患者中的每一位都检测到至少一项其他抗体形成异常。锡克试验是一种有助于评估免疫能力的简单筛查手段。
