Donshik P C, Cavanaugh H D, Boruchoff S A, Dohlman C H
Ann Ophthalmol. 1981 Jan;13(1):29-32.
Posterior subcapsular cataracts studied in 86 eyes of 86 patients transplanted for keratoconus were retrospectively studied. The follow-up period ranged between one and four years with a median of 18 months. Twenty-eight eyes developed posterior subcapsular cataracts. The development of posterior subcapsular cataracts was significantly related to the total cumulative steroid dose and the total time steroids were administered (p less than 0.01). Age, surgical technique, and rejection episodes could not be significantly correlated with development of a posterior cataract. The progression of the cataract appeared to be slow, and if topical steroids were discontinued the lens changes appeared to stabilize and progressed in only one patient. The effect of an early posterior subcapsular cataract on visual acuity was minimal in the early stages.
对86例圆锥角膜患者的86只移植眼进行了后囊下白内障的回顾性研究。随访时间为1至4年，中位数为18个月。28只眼发生了后囊下白内障。后囊下白内障的发生与类固醇的总累积剂量和使用类固醇的总时间显著相关（p<0.01）。年龄、手术技术和排斥反应与后发性白内障的发生无显著相关性。白内障的进展似乎较慢，如果停用局部类固醇，晶状体变化似乎会稳定下来，仅1例患者病情进展。早期后囊下白内障对视力的影响在早期最小。
