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药物诱导正常健康受试者E玫瑰花结形成细胞(RFC)减少。左旋咪唑和胸腺生成素五肽可使其恢复。

Pharmacological induced depression of E-rosette forming cells (RFC) of normal healthy subjects. Restoration by levamisole and thymopoietin pentapeptide.

作者信息

Laghi Pasini F, Auteri A, Ceccatelli L, Di Perri T

出版信息

Boll Soc Ital Biol Sper. 1980 Feb 29;56(4):316-22.

PMID:7018516
Abstract

The authors describe a pharmacological inhibition of E-Rosette formation by the "in vitro" addition of adenosine and theophylline. In the same experimental conditions TP5 and levamisole are able to reverse this inhibiting activity. The role of the cyclic nucleotides (cAMP and cGMP) in the regulation of the lymphocytes response is discussed.

摘要

作者描述了通过“体外”添加腺苷和茶碱对E-玫瑰花结形成的药理学抑制作用。在相同的实验条件下,TP5和左旋咪唑能够逆转这种抑制活性。文中讨论了环核苷酸(cAMP和cGMP)在调节淋巴细胞反应中的作用。

相似文献

1
Pharmacological induced depression of E-rosette forming cells (RFC) of normal healthy subjects. Restoration by levamisole and thymopoietin pentapeptide.药物诱导正常健康受试者E玫瑰花结形成细胞(RFC)减少。左旋咪唑和胸腺生成素五肽可使其恢复。
Boll Soc Ital Biol Sper. 1980 Feb 29;56(4):316-22.
2
Comparison of the in vitro effects of thymopoietin pentapeptide and levamisole on peripheral E-rosette forming cells.
Thymus. 1980 Jan;1(4-5):195-204.
3
Effect of thymopoietin pentapeptide on low reversible E-rosette forming cells of rheumatoid arthritis patients. -I) In vitro study.胸腺生成素五肽对类风湿关节炎患者低可逆性E玫瑰花结形成细胞的作用。-I) 体外研究。
Boll Soc Ital Biol Sper. 1980 Feb 29;56(4):308-11.
4
Effects of thymopoietin pentapeptide on low reversible E-rosette forming cells of rheumatoid arthritis patients.-II) In vivo study.胸腺生成素五肽对类风湿性关节炎患者低可逆性E玫瑰花结形成细胞的影响。-II)体内研究。
Boll Soc Ital Biol Sper. 1980 Feb 29;56(4):312-5.
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Restoration of the impaired lymphocyte stimulation in old people by thymopoietin pentapeptide.
J Clin Lab Immunol. 1981 Sep;6(2):103-5.
6
Influence of thymic hormones on mitogen-induced interferon production in lymphocytes. II. Enhancement of Con-A-induced immune interferon production by a synthetic thymopoietin pentapeptide.胸腺激素对淋巴细胞有丝分裂原诱导的干扰素产生的影响。II. 一种合成胸腺生成素五肽增强刀豆球蛋白A诱导的免疫干扰素产生
Arch Geschwulstforsch. 1984;54(2):113-8.
7
Immunokinetics of a single dose of thymopoietin pentapeptide.单剂量胸腺生成素五肽的免疫动力学
J Immunopharmacol. 1980;2(4):567-72. doi: 10.3109/08923978009026413.
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Induction and augmentation of mitogen-induced immune interferon production in human lymphocytes by a synthetic thymopoietin pentapeptide.
Biomed Biochim Acta. 1984;43(6):K9-12.
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Activities of purine nucleotide metabolizing enzymes in human thymocytes and peripheral blood T lymphocytes: in vitro effect of thymic hormones.人胸腺细胞和外周血T淋巴细胞中嘌呤核苷酸代谢酶的活性:胸腺激素的体外作用
Thymus. 1982 May;4(3):163-72.
10
Immunoregulating peptides II. In vitro effects of TP5 analogs on E-rosette formation and cell division.免疫调节肽II。TP5类似物对E花环形成和细胞分裂的体外作用。
Immunopharmacol Immunotoxicol. 1987;9(1):1-18. doi: 10.3109/08923978709035198.

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1
Quantitative histochemical studies of the effect of levamisole on splenic T-cells in thymectomized Bufo bufo larvae.
Cell Tissue Res. 1982;227(3):595-600. doi: 10.1007/BF00204789.