药物诱导正常健康受试者E玫瑰花结形成细胞（RFC）减少。左旋咪唑和胸腺生成素五肽可使其恢复。
Pharmacological induced depression of E-rosette forming cells (RFC) of normal healthy subjects. Restoration by levamisole and thymopoietin pentapeptide.
作者信息
Laghi Pasini F, Auteri A, Ceccatelli L, Di Perri T
出版信息
Boll Soc Ital Biol Sper. 1980 Feb 29;56(4):316-22.
PMID:7018516
Abstract
The authors describe a pharmacological inhibition of E-Rosette formation by the "in vitro" addition of adenosine and theophylline. In the same experimental conditions TP5 and levamisole are able to reverse this inhibiting activity. The role of the cyclic nucleotides (cAMP and cGMP) in the regulation of the lymphocytes response is discussed.
摘要
作者描述了通过“体外”添加腺苷和茶碱对E-玫瑰花结形成的药理学抑制作用。在相同的实验条件下，TP5和左旋咪唑能够逆转这种抑制活性。文中讨论了环核苷酸（cAMP和cGMP）在调节淋巴细胞反应中的作用。
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