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[钙与内分泌胰腺分泌。II. 静脉输注钙对静脉注射葡萄糖诱导的胰岛素和胰高血糖素分泌的影响]

[Calcium and endocrine pancreas secretion. II. Effects of an infusion of calcium on insulin and glucagon secretion induced by intravenous administration of glucose].

作者信息

Cucinotta D, Quartarone M, Longo G, Toscano A, Saitta A, Musolino C, Squadrito G

出版信息

Boll Soc Ital Biol Sper. 1980 Feb 29;56(4):339-45.

PMID:7018518
Abstract

IRI, IRG and blood glucose levels after I.V.G.T.T. in normal subjects were not significantly modified when I.V.G.T.T. was repeated during a prolonged calcium infusion (15 mg/Kg body weight per 90'). The Authors advance the hypothesis that no closed relationships exist between serum calcium levels and insulin secretion, in these experimental conditions; with regard to glucagon secretion, further experiences are of course required namely during alpha-cell stimulation.

摘要

在长时间输注钙(每90分钟15毫克/千克体重)期间重复进行静脉葡萄糖耐量试验(I.V.G.T.T.)时,正常受试者在I.V.G.T.T.后的缺血再灌注损伤(IRI)、胰岛素抵抗基因(IRG)和血糖水平没有显著改变。作者提出假说,即在这些实验条件下,血清钙水平与胰岛素分泌之间不存在密切关系;关于胰高血糖素分泌,当然还需要进一步的实验,即在α细胞刺激期间进行实验。

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