Welliver R C, Gallagher M R, Ogra P L
Crit Rev Clin Lab Sci. 1981;13(3):213-39. doi: 10.3109/10408368109106448.
Infection with RSV is one of the most common respiratory viral infections in childhood, particularly in infants under 1 year of age. The disease is characterized by epidemic proportions of infection which occur regularly in all parts of the world in the winter months. The spectrum of the clinical disease is quite variable, and the infection may present as bronchiolitis, pneumonia, croup, or exacerbation of pre-existing reactive airway disease. Recent evidence has suggested that RSV infection may be frequently associated with apnea in infancy and possibly sudden-infant-death syndrome. Although the laboratory diagnosis of this infection can be successfully accomplished by any well-known and conventional procedures, such as tissue culture infectivity and determination of serologic response, recently it has become possible to diagnose the infection very rapidly by application of such techiques as immunofluorescent staining and enzyme-linked immunonoabsorbent assay (ELISA).
呼吸道合胞病毒（RSV）感染是儿童时期最常见的呼吸道病毒感染之一，尤其是在1岁以下的婴儿中。该疾病的特点是感染呈流行态势，在世界所有地区的冬季都会定期出现。临床疾病的范围变化很大，感染可能表现为细支气管炎、肺炎、哮吼或既往存在的反应性气道疾病的加重。最近的证据表明，RSV感染可能经常与婴儿期呼吸暂停以及可能的婴儿猝死综合征相关。尽管通过任何知名的传统方法，如组织培养感染性和血清学反应测定，都可以成功完成这种感染的实验室诊断，但最近通过应用免疫荧光染色和酶联免疫吸附测定（ELISA）等技术，已经能够非常快速地诊断该感染。
