关于人晶状体膜主要内在多肽的免疫化学研究。
Immunochemical studies on the major intrinsic polypeptides from human lens membrane.
作者信息
Zigler J S, Horwitz J
出版信息
Invest Ophthalmol Vis Sci. 1981 Jul;21(1 Pt 1):46-51.
PMID:7019150
Abstract
Cell membranes from the human lens contain two major polypeptides with molecular weights near 26,000 and 22,000. These two species have been isolated in a highly purified state and purified by means of an antiserum against the 26,000 dalton membrane polypeptide from bovine lens. Immunochemical data are presented that establish a clear structural relationship between the two polypeptides and are consistent with the hypothesis that the 22,000 dalton species derived proteolytically from the 26,000 dalton species.
摘要
人晶状体的细胞膜含有两种主要的多肽，分子量分别接近26,000和22,000。这两种物质已被高度纯化，并通过抗牛晶状体26,000道尔顿膜多肽的抗血清进行纯化。文中给出的免疫化学数据表明这两种多肽之间存在明确的结构关系，并且与22,000道尔顿的物质是由26,000道尔顿的物质经蛋白水解产生的这一假设相一致。
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