母亲输注右旋糖酐铁后婴儿的细菌学反应受损。
Impaired bacteriological responses in babies after maternal iron dextran infusion.
作者信息
Webster M H, Waitkins S A, Stott A
出版信息
J Clin Pathol. 1981 Jun;34(6):651-4. doi: 10.1136/jcp.34.6.651.
Abstract
The effect of a total dose infusion of iron dextran in pregnancy on 15 mothers and their babies was compared with 19 controls. The bacteriostatic effect and opsonising ability of the sera, of babies born to the treated mothers, were considerably impaired. This was associated with a significantly lower transferrin concentration in these mothers. Although these in vitro tests were not associated with an increase in overt infection during the perinatal period, they suggest the need for caution in the use of total dose infusions in pregnancy.
摘要
将妊娠期间接受右旋糖酐铁总剂量输注的15位母亲及其婴儿的情况与19位对照者进行了比较。接受治疗的母亲所生婴儿血清的抑菌作用和调理能力显著受损。这与这些母亲体内转铁蛋白浓度明显较低有关。尽管这些体外试验并未显示围产期显性感染增加，但它们提示在妊娠期间使用总剂量输注时需谨慎。
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