Teramoto T, Nukina M, Koide M, Haruta T, Morikawa Y, Fujiwara T, Kobayashi Y
Jpn J Antibiot. 1981 Feb;34(2):200-4.
Group B Streptococcus was isolated from the clinical materials of the patients examined in the Kobe Central Municipal Hospital, in 1974 to 1979. 1. Clinical isolates were all resistant to bacitracin. 2. Serotypes of 19 isolates were type III in 12 strains, Ia in 3, Ic in 2 and untypable in 2. 3. The MICs were determined to 15 antibiotics, and the results showed that penicillin G was the best and in the order of decreasing potency, cefotaxime, ampicillin, ceftizoxime and cefoperazone. 4. Compared with group A Streptococcus, the sensitivity of group B Streptococcus to penicillin G and ampicillin was inferior by 2 to 3 tubes. 5. Based on the above results, the significance of the cephalosporin antibiotic of the third generation, particularly cefotaxime, was evaluated in the treatment of infectious diseases of the newborn infants.
1974年至1979年期间,在神户中央市立医院接受检查的患者临床材料中分离出B族链球菌。1. 临床分离株均对杆菌肽耐药。2. 19株分离株的血清型中,12株为III型,3株为Ia型,2株为Ic型,2株无法分型。3. 测定了15种抗生素的最低抑菌浓度(MIC),结果表明青霉素G效果最佳,效力递减顺序为头孢噻肟、氨苄西林、头孢唑肟和头孢哌酮。4. 与A族链球菌相比,B族链球菌对青霉素G和氨苄西林的敏感性低2至3管。5. 根据上述结果,评估了第三代头孢菌素抗生素,特别是头孢噻肟在新生儿传染病治疗中的意义。