Scaffidi L, Scaffidi A
Minerva Med. 1981 Sep 1;72(31):2085-96.
The typical papulomacular picture of boutonneuse fever is described. A series of atypical exanthemas is presented: simply erythemato-macular and typhus-like, nodular, vesicular. Skin biopsies showing the endothelial, thrombotic and parietal aspects of periadventitial infiltration (this being sometimes moderately and extensively pericapillary) are also presented. The reason for the absence of extensive thrombisation in extensive, marked rickettsiotic endothelitis are discussed, and stress is laid to the hitherto little-discussed, but significant involvement of dermal collagen.
描述了纽扣热典型的丘疹斑疹表现。还展示了一系列非典型皮疹:单纯红斑疹和斑疹伤寒样、结节状、水疱状。还展示了皮肤活检显示血管外膜浸润的内皮、血栓形成和壁层方面(有时为中等程度且广泛的毛细血管周围浸润)。讨论了在广泛、明显的立克次体性内皮炎症中缺乏广泛血栓形成的原因,并强调了迄今讨论较少但重要的真皮胶原受累情况。