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慢性血吸虫性尿路病的放射性核素研究

Radionuclide studies of chronic schistosomal uropathy.

作者信息

Lamki L M, Lamki N

出版信息

Radiology. 1981 Aug;140(2):471-4. doi: 10.1148/radiology.140.2.7019960.

DOI:10.1148/radiology.140.2.7019960
PMID:7019960
Abstract

Fifty patients with chronic urinary tract schistosomiasis were studied with 99mTc-DTPA. All had a flow study, sequential analog imaging, and digital imaging for 25-35 minutes (20-sec. frames). Time-activity curves (DTPA renograms) were extracted; 12 patients had 131I-Hippuran probe renograms as well. Renal changes included diminished perfusion and structural abnormalities ranging from minor calyceal dilatation to overt hydronephrosis. Ureteral changes included dilatation, tortuosity, and kinking. Marked distortion of the ureterovesical junction was seen in some patients due to periureteral and perivesicular fibrosis, which is a major factor in upper urinary tract damage. Renograms showed varying obstruction and parenchymal damage. Nuclear medicine complements excretory urography and is sometimes preferable for visualization of the ureters. After the initial urogram, sequential DTPA scanning and renography are sufficient for follow-up.

摘要

对50例慢性尿路血吸虫病患者进行了99mTc-DTPA研究。所有患者均进行了血流研究、连续模拟成像和25 - 35分钟(每帧20秒)的数字成像。提取了时间 - 活性曲线(DTPA肾图);12例患者还进行了131I - 马尿酸盐探头肾图检查。肾脏改变包括灌注减少和结构异常,范围从小盏扩张到明显的肾积水。输尿管改变包括扩张、迂曲和扭结。部分患者可见输尿管膀胱连接处因输尿管周围和膀胱周围纤维化而出现明显变形,这是上尿路损伤的主要因素。肾图显示出不同程度的梗阻和实质损害。核医学可补充排泄性尿路造影,有时在输尿管显影方面更具优势。在最初的尿路造影后,连续的DTPA扫描和肾图检查足以进行随访。

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