Alepee B, Cava E, Babo P, Accard J L, Marsan C
Rev Fr Mal Respir. 1981;9(2):133-45.
A series of 132 bronchial brushings studied according to a strict protocol, both in obtaining the specimens and their subsequent laboratory preparation, has allowed us to study the cells of the bronchial mucosa in greater detail. Until now the greater part of the work in this field has been on the characteristics of tumour cells and the variability in detecting cancer, slightly neglecting the analysis of normal, inflammatory or dystrophic cells. The brushings were compared to the cytology requests on sputum and/or corresponding aspirations by conventional methods. This work has shown that the different types of normal epithelial cells so recovered, as well as dystrophic cells, have a very different appearance than those same cells when observed using classical cytological methods (on sputa and aspirations). The cyto-pathologist ought to adjust the technique before interpreting the specimens. The differences are due to a better state of conservation of the recovered cells, thanks to improvement in current endoscopic technique. We infer that certain cytological appearances considered pathological until now, using classical expectoration or aspiration, may in reality only be artefacts.
按照严格的方案对132例支气管刷检样本进行了研究，从样本采集到后续实验室制备的整个过程，使我们能够更详细地研究支气管黏膜细胞。到目前为止，该领域的大部分工作都集中在肿瘤细胞的特征以及癌症检测的变异性上，而在一定程度上忽略了对正常、炎症或营养不良细胞的分析。通过传统方法将刷检样本与痰和/或相应抽吸物的细胞学检查需求进行比较。这项研究表明，如此回收的不同类型的正常上皮细胞以及营养不良细胞，与使用经典细胞学方法（对痰液和抽吸物）观察时的相同细胞相比，外观有很大差异。细胞病理学家在解释样本之前应调整技术。这些差异归因于当前内镜技术的改进，使回收细胞的保存状态更好。我们推断，迄今为止使用经典咳痰或抽吸法认为是病理性的某些细胞学表现，实际上可能只是人为现象。
