• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Influence of culture conditions on B-cell functions in vitro.

作者信息

Ziegler B, Wilke B, Woltanski P

出版信息

Acta Biol Med Ger. 1981;40(1):97-8.

PMID:7020311
Abstract

Isolated pancreatic islets from Wistar rats were maintained in vitro at 37 degrees C for 12 days in TCM 199 containing 10 mmol/l glucose and supplemented with 10% serum. 10 mmol/l glucose completely prevented the diminution of insulin content independent of the type of serum (fetal calf serum; serum from newborn calfs; horse serum), whereas the insulin biosynthesis as well as the insulin release were modulated by the kind of serum. Fetal calf serum can be replaced by horse serum.

摘要

相似文献

1
Influence of culture conditions on B-cell functions in vitro.
Acta Biol Med Ger. 1981;40(1):97-8.
2
Growth hormone regulation of DNA replication, but not insulin production, is partly mediated by somatomedin-C/insulin-like growth factor I in isolated pancreatic islets from adult rats.生长激素对DNA复制的调节作用(而非胰岛素分泌),部分是由成年大鼠分离胰岛中的生长调节素-C/胰岛素样生长因子I介导的。
Diabetologia. 1989 Mar;32(3):191-7. doi: 10.1007/BF00265093.
3
[Functional morphology of the secretion process of islets of Langerhans B cells].
Verh Anat Ges. 1976(70 Pt 1):19-38.
4
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.大鼠胰岛长期暴露于脂肪酸会通过葡萄糖脂肪酸循环抑制葡萄糖诱导的胰岛素分泌和生物合成。
J Clin Invest. 1994 Feb;93(2):870-6. doi: 10.1172/JCI117042.
5
In vitro regulation of insulin release and biosynthesis of fetal rat pancreatic cells explanted on pregnancy day 16.妊娠第16天取出的胎鼠胰腺细胞胰岛素释放和生物合成的体外调节
Biol Neonate. 1997;71(1):60-8. doi: 10.1159/000244398.
6
Effects of growth hormone in vitro on the glucose metabolism of fetal rat islet beta-cells.
J Mol Endocrinol. 1996 Oct;17(2):131-8. doi: 10.1677/jme.0.0170131.
7
Effect of chloroquine on biosynthesis, release and degradation of insulin in isolated islets of rat pancreas.氯喹对大鼠胰腺分离胰岛中胰岛素生物合成、释放及降解的影响。
Diabetes Res Clin Pract. 1988 May 19;5(1):9-15. doi: 10.1016/s0168-8227(88)80072-x.
8
In vitro restoration of insulin production in islets from adult rats treated neonatally with streptozotocin.新生期用链脲佐菌素处理的成年大鼠胰岛中胰岛素生成的体外恢复
Endocrinology. 1990 Apr;126(4):1842-8. doi: 10.1210/endo-126-4-1842.
9
Interleukin-6 affects insulin secretion and glucose metabolism of rat pancreatic islets in vitro.白细胞介素-6在体外影响大鼠胰岛的胰岛素分泌和葡萄糖代谢。
Endocrinology. 1990 Feb;126(2):1288-94. doi: 10.1210/endo-126-2-1288.
10
Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans.长期暴露于脂肪酸和酮会抑制人类胰岛朗格汉斯细胞中B细胞的功能。
J Clin Endocrinol Metab. 1995 May;80(5):1584-90. doi: 10.1210/jcem.80.5.7745004.