核糖体肽基转移酶的供体部位：以2'（3'）-O-（N-酰基氨基酰基）二核苷磷酸作为N-酰基氨基酰基转移核糖核酸3'末端模型研究底物特异性 - Suppr

Donor site of ribosomal peptidyltransferase: investigation of substrate specificity using 2'(3')-O-(N-acylaminoacyl)dinucleoside phosphates as models of the 3' terminus of N-acylaminoacyl transfer ribonucleic acid.

作者信息

Quiggle K, Kumar G, Ott T W, Ryu E K, Chládek S

出版信息

Biochemistry. 1981 Jun 9;20(12):3480-5. doi: 10.1021/bi00515a027.

DOI:10.1021/bi00515a027

PMID:7020753

Abstract

摘要

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Donor site of ribosomal peptidyltransferase: investigation of substrate specificity using 2'(3')-O-(N-acylaminoacyl)dinucleoside phosphates as models of the 3' terminus of N-acylaminoacyl transfer ribonucleic acid.

Biochemistry. 1981 Jun 9;20(12):3480-5. doi: 10.1021/bi00515a027.

Kinetic constants for model substrates of peptidyltransferase donor site of Escherichia coli ribosomes.

FEBS Lett. 1979 Aug 15;104(2):279-83. doi: 10.1016/0014-5793(79)80832-7.

Stereochemical control of the ribosomal peptidyltransferase reaction. The role of acceptor substrate amino acid side chain orientation.

FEBS Lett. 1978 Dec 1;96(1):23-5. doi: 10.1016/0014-5793(78)81053-9.

On substrate specificity of the donor site of the Escherichia coli ribosomal peptidyl transferase center. Synthesis of dipeptides from 3'-terminal fragments of aminoacyl-tRNA.

FEBS Lett. 1982 Jun 1;142(1):96-100. doi: 10.1016/0014-5793(82)80227-5.

Cooperative binding of 3'-fragments of transfer ribonucleic acid to the peptidyltransferase center of Escherichia coli ribosomes.

Arch Biochem Biophys. 1978 Sep;190(1):149-54. doi: 10.1016/0003-9861(78)90262-x.

The donor site of the peptidyltransferase center of ribosomes: equilibrium association constants of model substrates and inhibitors.

FEBS Lett. 1979 Jun 1;102(1):198-203. doi: 10.1016/0014-5793(79)80959-x.

[The peptidyltransferase center of ribosomes--what is it?].

Mol Biol (Mosk). 1985 Mar-Apr;19(2):371-7.

[Donor site of E. coli ribosomal peptidyltransferase].

Mol Biol (Mosk). 1976 Nov-Dec;10(6):1394-402.

The role of the cytidine residues of the tRNA 3'-terminus at the peptidyltransferase A- and P-sites.

FEBS Lett. 1980 Sep 8;118(2):172-5. doi: 10.1016/0014-5793(80)80212-2.

The peptidyltransferase center of ribosomes.

Prog Nucleic Acid Res Mol Biol. 1979;23:1-51. doi: 10.1016/s0079-6603(08)60130-0.

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Solid phase synthesis and binding affinity of peptidyl transferase transition state mimics containing 2'-OH at P-site position A76.

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Donor site of ribosomal peptidyltransferase: investigation of substrate specificity using 2'(3')-O-(N-acylaminoacyl)dinucleoside phosphates as models of the 3' terminus of N-acylaminoacyl transfer ribonucleic acid.

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