García E Silva L, Coelho M R
Med Cutan Ibero Lat Am. 1981;9(1):1-9.
Seventy seven angioleiomyomata from 75 patients, 19 males and 55 females, are reviewed. One patient had 2 lesions and another a local recurrence after surgical excision. Only 3 were less than 20 years old and most were beyond 30 (average age 47). Fifty four lesions were on the lower limbs, 4 on the head and legs), 9 on the upper limbs, 4 on the head and 1 on the trunk. The size of the lesions varied from a pepper grain to a pigeon egg but most were pea sized. The more significant symptom was pain, present in at least 58% of the lesions, and responsible for the diagnosis, often made, of neurofibroma, neuroma, glomus tumour and leiomyoma. Its intensity was variable and could be induced by mechanical or thermal stimuli or even arise spontaneously. Histologically the tumour was usually a deep dermal or hypodermal, well defined, ovoid or round shaped, compact nodule, composed of smooth muscle fibers often disposed around variously shaped vascular lumina. Clinical and histological similarities to glomus tumours as well as the occasional coexistence of both lesions point to a common origin from the myoarterial glomus or from a closely related arteriovenous anastomosis. The relevant features in our series are compared with those reported in the literature and their similarities and differences are discussed.
对来自75例患者的77例血管平滑肌瘤进行了回顾性研究,其中男性19例,女性55例。1例患者有2个病灶,另1例在手术切除后出现局部复发。只有3例患者年龄小于20岁,大多数患者年龄超过30岁(平均年龄47岁)。54个病灶位于下肢,4个位于头部和腿部,9个位于上肢,4个位于头部,1个位于躯干。病灶大小从胡椒粒到鸽蛋不等,但大多数为豌豆大小。更明显的症状是疼痛,至少58%的病灶有疼痛症状,这也是常被诊断为神经纤维瘤、神经瘤、球瘤和平滑肌瘤的原因。疼痛强度各异,可由机械或热刺激诱发,甚至可自发出现。组织学上,肿瘤通常为深部真皮或皮下的、边界清晰的、卵圆形或圆形的致密结节,由围绕各种形状血管腔排列的平滑肌纤维组成。与球瘤的临床和组织学相似性以及两种病灶偶尔并存表明它们起源于肌动脉球或密切相关的动静脉吻合。将我们系列中的相关特征与文献报道的特征进行了比较,并讨论了它们的异同。