Jehn U, Clemm C, Wilmanns W
Onkologie. 1981 Apr;4(2):60-72. doi: 10.1159/000214881.
58 adult patients with acute leukemia were analyzed in respect to the rate of first remission induction, remission duration, survival, and treatment of relapse. A selection of subgroups has been avoided to reflect clinical reality. Although our results of remission induction were slightly under those reported from other groups, the duration of remission and survival was favorably comparable. The prognostic value of LDH and systemic infection on admission for the outcome of the disease has been evaluated. Selective decontamination of the G.I.-tract reduced the rate of life-threatening infections and increased the rate of complete remissions significantly. LDH was of no importance in predicting the likelihood of achieving complete remission or duration of complete remission.
对58例成年急性白血病患者的首次缓解诱导率、缓解持续时间、生存率及复发治疗情况进行了分析。为反映临床实际情况，未对亚组进行选择。虽然我们的缓解诱导结果略低于其他组报道的结果，但缓解持续时间和生存率具有良好的可比性。评估了乳酸脱氢酶（LDH）和入院时全身感染对疾病预后的价值。胃肠道选择性去污降低了危及生命感染的发生率，并显著提高了完全缓解率。LDH在预测完全缓解的可能性或完全缓解的持续时间方面并不重要。
