Taenzer V, Albrecht A, Clauss W, Held I
Radiologe. 1981 Jun;21(6):288-90.
Tolerance of two contrast media was compared by a double blind study. High doses of iodine (45 g) were used for both contrast substances. Sodium Ioglicinate was giving best radiological contrast but produced more side-effects, especially nausea, as compared to Methylglucamine-Ioglicinate. On the contrary Methylglucamine-Ioglicinate did not give best density but did produce less side-effects. Thus the investigator has to consider very carefully, which of the compounds has to be preferred.
通过双盲研究比较了两种造影剂的耐受性。两种造影剂均使用了高剂量碘(45克)。与碘葡胺甲基葡胺盐相比,碘葡酸钠产生的放射学对比度最佳,但副作用更多,尤其是恶心。相反,碘葡胺甲基葡胺盐的密度不是最佳,但副作用较少。因此,研究人员必须非常仔细地考虑哪种化合物更可取。