Kinoshita S, Friend J, Thoft R A
Invest Ophthalmol Vis Sci. 1981 Sep;21(3):434-41.
The survival of donor corneal epithelium was investigated in rabbits after they received unilateral 8 mm diameter lamellar keratoplasties with living donor tissue of a different sex from the host. Three weeks, 6 weeks, and 12 weeks postoperatively, cultured corneal epithelia, grown from 5 mm diameter central buttons, the adjacent 0.75 mm wide donor rings, the peripheral 10 to 13 mm diameter rings, and 5 mm diameter central host buttons were used for sex-chromatin analysis. The results indicated that some of the donor corneal epithelium survived up to 12 weeks postoperatively. Even in the absence of overt epithelial rejection, however, a time-dependent decrease of donor corneal epithelium and simultaneous invasion of host corneal epithelium were demonstrated.
在兔接受与宿主不同性别的活体供体组织进行单侧直径8毫米板层角膜移植术后，对供体角膜上皮的存活情况进行了研究。术后3周、6周和12周，从直径5毫米的中央纽扣、相邻的0.75毫米宽的供体环、直径10至13毫米的周边环以及直径5毫米的中央宿主纽扣培养的角膜上皮用于性染色质分析。结果表明，部分供体角膜上皮在术后存活长达12周。然而，即使在没有明显上皮排斥反应的情况下，也证实了供体角膜上皮随时间减少以及宿主角膜上皮同时侵入的现象。
