Fleischmann J, Perinetti E P, Catalona W J
J Urol. 1981 Sep;126(3):389-92. doi: 10.1016/s0022-5347(17)54539-5.
We report on 14 patients with embryonal rhabdomyosarcoma of the genitourinary organs treated with combined modality therapy. Six patients with paratesticular lesions are free of tumor 7 to 72 months (mean 44) after diagnosis, while 6 of 8 with pelvic lesions are free of tumor 18 to 132 months (mean 61) following diagnosis. Two patients died of metastases. Over-all, 2-year survival free of relapse was obtained in 9 of 11 patients (81 per cent). Of 4 patients with pelvic lesions who were treated with primary radiation-chemotherapy without exenteration 3 were managed successfully but 1 required urinary diversion for vesical fibrosis. Current concepts in the management of embryonal rhabdomyosarcoma are discussed.
我们报告了14例接受综合治疗的泌尿生殖器官胚胎性横纹肌肉瘤患者。6例睾丸旁病变患者在诊断后7至72个月（平均44个月）无肿瘤，而8例盆腔病变患者中有6例在诊断后18至132个月（平均61个月）无肿瘤。2例患者死于转移。总体而言，11例患者中有9例（81%）获得了2年无复发存活。4例接受原发性放化疗而未行脏器去除术的盆腔病变患者中，3例治疗成功，但1例因膀胱纤维化需要进行尿流改道。本文讨论了胚胎性横纹肌肉瘤治疗的当前理念。
