Wilson R G
J S Afr Vet Assoc. 1978 Mar;49(1):49-51.
Three general biochemical mechanisms can cause ticks to be resistant to acaricides: an alteration in the properties of the site of action, a change in the rate of transportation and a change in the rate of metabolism. The first mechanism enables increased concentrations of acaricide at the site of action to be tolerated, while the last two mechanisms result in a decreased concentration and/or persistence of the acaricide at the site of action. These mechanisms are discussed in detail with reference to a range or acaricides, particular emphasis being given to blue tick strains occurring in Southern Africa.
作用位点特性的改变、转运速率的变化和代谢速率的变化。第一种机制能使作用位点耐受更高浓度的杀螨剂,而后两种机制则导致作用位点处杀螨剂的浓度降低和/或存留时间缩短。本文结合一系列杀螨剂对这些机制进行了详细讨论,特别强调了在南部非洲出现的蓝蜱菌株。