大鼠尿道球腺的生化组成

Biochemical Composition of rat Cowper's gland.

作者信息

Srivastava S R, Sheth A R, Dasgupta P R

出版信息

Andrologia. 1981 Jul-Aug;13(4):363-8. doi: 10.1111/j.1439-0272.1981.tb00065.x.

DOI:10.1111/j.1439-0272.1981.tb00065.x

Abstract

Cowper's glands of rats were analysed for ten different biochemical parameters including enzymes and substrates under different hormonal status of the animals. Sialic acid, glycogen and activities of maltase and alkaline phosphatase enzymes of the prepuberal glands were found to be elevated to the levels of the adult (control animals) after treatment with testosterone propionate. On the other hand, following castration of adult animals a dramatic fall of the maltase activity of the gland was recorded; other parameters studied also registered a significant fall from their normal values. However, following treatment with testosterone propionate of the castrate animals all parameters excepting total lipids and phospholipids were found to recover. Sialic acid of the prepuberal animals and maltase activity of the adult were highly sensitive to testosterone propionate.

摘要

对处于不同激素状态的大鼠的考珀氏腺进行了十种不同生化参数的分析，包括酶和底物。发现经丙酸睾酮处理后，青春期前腺体的唾液酸、糖原以及麦芽糖酶和碱性磷酸酶的活性升高至成年（对照动物）水平。另一方面，成年动物去势后，腺体的麦芽糖酶活性显著下降；所研究的其他参数也从其正常值大幅下降。然而，给去势动物注射丙酸睾酮后，除总脂质和磷脂外的所有参数均恢复。青春期前动物的唾液酸和成年动物的麦芽糖酶活性对丙酸睾酮高度敏感。