Mimran A
Nouv Presse Med. 1981 Apr 30;10(19):1594-5.
The angiotensin-converting enzyme inhibitor captopril (SQ 14225, 50 mg tid) was used for treating a patient with idiopathic edema. A marked improvement of clinical condition was achieved as confirmed by the significant decrease in the morning-evening weight difference during treatment. No disturbance of arterial pressure regulation as well as side effects were observed after a 22 month-period of treatment. This observation which needs further studies brings a new approach of the treatment of patients with idiopathic edema.
血管紧张素转换酶抑制剂卡托普利(SQ 14225,50毫克,每日三次)用于治疗一名特发性水肿患者。治疗期间早晚体重差值显著降低,证实临床状况有明显改善。经过22个月的治疗,未观察到动脉血压调节紊乱以及副作用。这一观察结果需要进一步研究,为特发性水肿患者的治疗带来了新方法。