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逼尿肌-括约肌协同失调及协同失调反应:完全性脊髓损伤病变中早期改良经尿道括约肌切开术的识别及理论依据

Detrusor-sphincter dyssynergia and dyssynergic responses: recognition and rationale for early modified transurethral sphincterotomy in complete spinal cord injury lesions.

作者信息

Perkash I

出版信息

J Urol. 1978 Oct;120(4):469-74. doi: 10.1016/s0022-5347(17)57233-x.

Abstract

Some characteristics are described for detrusor-sphincter dyssynergia and the dyssynergic response in spinal injury patients with complete lesions. The urodynamic evaluation and clinical problems are analyzed in 53 patients to identify the importance of early recognition of sphincter dyssynergia. Cystomanometric and urethral profile pressures vary from 30 to 150 cm. water. Although high voiding pressure, particularly associated with autonomic dysreflexia, may be indicative of sphincter dyssynergia it is not diagnostic. Relevant characteristics of patients with detrusor-sphincter dyssynergia are 1) rhythmic detrusor contractions on cystomanometry with associated marked increase in electromyographic activity on attempted voiding. These characteristics enable early recognition of dyssynergia and afford expediency in its management. The modified approach to external sphincterotomy as practiced by the author provides optimal surgical approach for urological rehabilitation of dyssynergic patients. Thus, the rationale for characterization of dyssynergia and its management by modified sphincterotomy can help to terminate long-term intermittent catheterization, remove indwelling catheter, prevent renal damage and ameliorate autonomic dysreflexia.

摘要

本文描述了完全性脊髓损伤患者逼尿肌-括约肌协同失调及协同失调反应的一些特征。对53例患者的尿动力学评估和临床问题进行了分析,以确定早期识别括约肌协同失调的重要性。膀胱测压和尿道压力曲线压力在30至150厘米水柱之间变化。虽然高排尿压力,特别是与自主神经反射异常相关的高排尿压力,可能提示括约肌协同失调,但它并非诊断依据。逼尿肌-括约肌协同失调患者的相关特征为:1)膀胱测压时逼尿肌有节律性收缩,同时在试图排尿时肌电图活动显著增加。这些特征有助于早期识别协同失调,并为其治疗提供便利。作者采用的改良外括约肌切开术方法为协同失调患者的泌尿外科康复提供了最佳手术途径。因此,对协同失调进行特征描述并通过改良括约肌切开术进行治疗的基本原理有助于终止长期间歇性导尿、拔除留置导尿管、预防肾损伤并改善自主神经反射异常。

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