Sindelar W F, Bagley D H, Felix E L, Doppman J L, Ketcham A S
JAMA. 1978 Nov 3;240(19):2060-3.
In a retrospective study of the cases of 415 patients with various malignant neoplasms, full-lung tomography and conventional chest roentgenography were compared for accuracy in the detection of pulmonary metastases. Sufficient information was available on 410 patients to permit confirmation as to whether pulmonary metastases were present at the time of screening chest roentgenographic and tomographic examinations. On screening by routine chest roentgenography, metastases were detected in 36 patients, 66.7% of the total with confirmed metastatic disease. Screening by full-lung tomography identified metastases in 51 (94.4%). Fifteen patients with normal chest roentgenograms had metastatic lesions on tomograms. Metastases were detected in 8.8% by chest roentgenograms and in 12.4% by tomograms in a population of cancer patients with a 13.2% incidence of pathologically confirmed metastatic lesions.
在一项对415例患有各种恶性肿瘤患者的回顾性研究中,比较了全肺断层扫描和传统胸部X线摄影在检测肺转移方面的准确性。有410例患者可获得足够信息,以确认在进行胸部X线摄影和断层扫描筛查时是否存在肺转移。通过常规胸部X线摄影进行筛查时,在36例患者中检测到转移,占确诊转移性疾病患者总数的66.7%。通过全肺断层扫描进行筛查时,有51例(94.4%)检测到转移。15例胸部X线片正常的患者在断层扫描上有转移病灶。在一组病理确诊转移性病变发生率为13.2%的癌症患者中,胸部X线片检测到转移的比例为8.8%,断层扫描检测到转移的比例为12.4%。