Melet J J
Phlebologie. 1981 Jul-Sep;34(3):469-88.
The author reminds us that varicose veins involve a large social and financial cost. He states the the etiopathogenic hypotheses commonly suggested have not been confronted with geographic pathological data and that consequently they are of little value. A thorough study of the epidemiological data and clinical characteristics of the disease was made. The different factors which are considered or which are likely to be considered in the onset of varicose veins are investigated in light of these data. From this comparison, it appears that the Western diet is the fundamental cause of varicose inducement and that it leaves the other factors (predisposing, triggering or aggravating) as risk factors. The part it plays is probably due to a slight vitamin E deficiency which, once aggravated (during pregnancy for instance), would act upon venous walls, coagulation and fibrinolysis. Thus, the veins would become sensitive to blood stasis and to venous hypertension effects due in particular to constipation.
作者提醒我们，静脉曲张涉及巨大的社会和经济成本。他指出，通常提出的病因假说尚未与地理病理学数据相对照，因此其价值不大。对该疾病的流行病学数据和临床特征进行了全面研究。根据这些数据，对静脉曲张发病中被考虑或可能被考虑的不同因素进行了调查。通过这种比较，似乎西方饮食是导致静脉曲张的根本原因，而其他因素（ predisposing、triggering或aggravating ）则为风险因素。其起作用的部分原因可能是维生素E轻微缺乏，一旦加重（例如在怀孕期间），就会作用于静脉壁、凝血和纤维蛋白溶解。因此，静脉会变得对血液瘀滞以及特别是由于便秘导致的静脉高压效应敏感。
