Suslov A P, Riabykh T P
Biull Eksp Biol Med. 1981 Jul;92(7):85-7.
Intact mice showed circadian rhythms of changes (pulsations) in the weight of the lymphoid organs, in the number of nuclear cells, as well as in the activity of serum factor(s) modifying lymphocyte migration in vitro. The pulsations were manifested by a short-term (over 1-4 h) twofold increase in the weight of the thymus, spleen and lymph nodes and in the number of cells contained by these organs. Sera from the animals with the enlarged organs inhibited the migration of thymocytes and spleen cells in vitro. The increased migration followed the maximal weight and the maximal number of cells of the lymphoid organs. It is suggested that pulsations seen in the lymphoid organs might reflect the mechanism of lymphocyte recirculation monitored by humoral mediators.
完整的小鼠显示出淋巴器官重量、核细胞数量以及体外修饰淋巴细胞迁移的血清因子活性的昼夜节律变化（波动）。这些波动表现为胸腺、脾脏和淋巴结重量以及这些器官所含细胞数量在短时间内（1至4小时以上）增加两倍。来自器官肿大动物的血清在体外抑制胸腺细胞和脾细胞的迁移。迁移增加发生在淋巴器官重量和细胞数量达到最大值之后。有人认为，在淋巴器官中观察到的波动可能反映了由体液介质监测的淋巴细胞再循环机制。
