Silberbauer K, Fitscha P, Sinzinger H
Wien Klin Wochenschr. 1981 Oct 2;93(18):577-9.
The incubation of rabbit venous rings (vena cava) is followed by the synthesis and release of prostacyclin (prostaglandin I2, PGI2), as measured by the inhibition of ADP-induced platelet aggregation. The incubation of the venous rings in dihydroergotamine leads to a stimulation of PGI2 synthesis and/or release. This effect of dihydroergotamine, apart from the vasoactive properties of this compound, might prove advantageous as a prophylactic measure in venous thrombosis.
兔静脉环（腔静脉）孵育后会合成并释放前列环素（前列腺素I2，PGI2），这可通过抑制ADP诱导的血小板聚集来测定。静脉环在双氢麦角胺中孵育会导致PGI2合成和/或释放受到刺激。双氢麦角胺的这种作用，除了该化合物的血管活性特性外，可能作为静脉血栓形成的一种预防措施被证明是有益的。
