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[T1b NO MO期宫颈癌根治术后放疗的问题。一项随机临床试验的初步结果]

[Problems of radiotherapy in radically removed cervix cancers in stages T1b NO MO. Preliminary results of a randomized clinical trial].

作者信息

Bilek K, Ebeling K, Leitsmann H, Seidel G

出版信息

Zentralbl Gynakol. 1981;103(17):1014-22.

PMID:7029975
Abstract

A prospective controlled study was undertaken for the purpose of establishing the usefulness of postoperative radiotherapy following radical surgery of cervical carcinoma, Stage pT1b NO MO. A random selection was made of 120 patients who were either treated exclusively by radical surgery (Wertheim-Meigs) or in whom radical surgery was followed by postoperative telecobalt irradiation of the minor pelvis 50 to 52 Gy). No significantly difference were found to exist between the two therapeutic approaches, after an average period of follow-up observations of 33 months (between twelve and 60 months). The incidence of lymphoedema was increased with significance in those patients who had been irradiated.

摘要

为确定宫颈癌pT1b NO MO期根治性手术后进行术后放疗的有效性,开展了一项前瞻性对照研究。随机选择120例患者,其中一部分仅接受根治性手术(韦特海姆-梅格斯手术),另一部分在根治性手术后接受小骨盆区域的术后远距钴放疗(50至52戈瑞)。经过平均33个月(12至60个月)的随访观察,发现两种治疗方法之间没有显著差异。接受放疗的患者中,淋巴水肿的发生率显著增加。

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Zentralbl Gynakol. 1981;103(17):1014-22.
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