Eliseenko V I, Skobelkin O K, Titova T M
Arkh Patol. 1981;43(9):43-50.
Morphological changes in the stomach of 40 heparinized dogs with acute gastric hemorrhages from experimental ulcers and 22 patients with acute gastrointestinal hemorrhages were studied immediately and at remote intervals after laser photocoagulations performed by continuous laser irradiation. After laser irradiation, typical changes in morphological structures developed and were accompanied by the appearance at the site of the bleeding ulcers of coagulation necrosis and coagulative thrombi of arrosive arteries conducive to hemostasis. Laser wounds healed with the formation of aseptic productive inflammation without considerable inflammatory infiltration and edema of the adjacent tissues. Reparation of the mucous membrane ends by 30--45 days after coagulation with regeneration of the muscular layer of the mucosa and without any scar in the submucous layer.
对40只经肝素化处理、因实验性溃疡导致急性胃出血的犬以及22例急性胃肠道出血患者,在连续激光照射进行激光光凝后即刻及远期进行了研究,观察其胃部的形态学变化。激光照射后,形态学结构出现典型改变,同时在出血性溃疡部位出现有利于止血的凝固性坏死以及糜烂动脉的凝血血栓。激光伤口愈合时形成无菌性增生性炎症,相邻组织无明显炎性浸润及水肿。黏膜修复在凝固后30 - 45天完成,黏膜肌层再生,黏膜下层无任何瘢痕。