Iisalo E U, Kanto J H
Int J Clin Pharmacol Ther Toxicol. 1981 Jun;19(6):260-5.
Dioxonium (30, 40, and 60 microgram/kg i.v.), a new depolarizing agent, weas compared with pancuronium (0.05 and 0.1 mg/kg i.v.) as a muscle relaxant in combination anesthesia during general surgical operations in small children. Generally, the conditions during intubation, maintenance of anesthesia, and in the recovery room were comparable after both drugs. There were no differences in the cardiovascular responses either. However, a wider intra- and interindividual variation in the drug response was observed after dioxonium, especially after repeated administrations.
二氧铵（静脉注射30、40和60微克/千克）是一种新型去极化剂，在小儿普通外科手术的复合麻醉中，作为肌肉松弛剂与潘库溴铵（静脉注射0.05和0.1毫克/千克）进行了比较。一般来说，两种药物给药后，插管、麻醉维持及恢复室期间的情况相当。心血管反应也无差异。然而，二氧铵给药后，尤其是重复给药后，观察到药物反应在个体内和个体间的差异更大。
