Beckman E N, Leonard G L, Castillo L E, Genre C F, Pankey G A
Am J Clin Pathol. 1981 Dec;76(6):765-72. doi: 10.1093/ajcp/76.6.765.
Although marine vibrio wound infections and septicemia are being reported with increasing frequency, description of the histopathologic changes has been scanty. The histologic alterations in three patients with primary marine vibrio wound infections are presented. The lesions are characterized by intense acute cellulitis of the subcutis with much tissue destruction and extension into the adjacent dermis. The superficial dermis is devitalized and lacks an inflammatory cellular infiltrate. Subepidermal noninflammatory bullae are formed. Many organisms are seen both within the areas of intense acute inflammation and in devitalized areas. Organisms and inflammation are especially oriented around vessels, with associated acute vasculitis. It is concluded that the morphologic picture in marine vibrio wound infections is nonspecific yet characteristic.
尽管海洋弧菌伤口感染和败血症的报告频率日益增加，但关于其组织病理学变化的描述却很少。本文介绍了3例原发性海洋弧菌伤口感染患者的组织学改变。病变的特征是皮下组织出现严重的急性蜂窝织炎，伴有大量组织破坏并蔓延至邻近的真皮层。浅表真皮失去活力，缺乏炎性细胞浸润。形成表皮下非炎性大疱。在严重急性炎症区域和失活区域均可见到许多细菌。细菌和炎症尤其围绕血管分布，并伴有急性血管炎。结论是海洋弧菌伤口感染的形态学表现虽无特异性，但具有特征性。
