Ohta T, Kato R, Boku K, Kondo M, Kazui H, Naiki K, Tsuchioka H, Inoue Y, Noguchi H, Takumi Y
Second Department of Surgery, Aichi Medical University.
Jpn J Surg. 1988 Sep;18(5):580-7. doi: 10.1007/BF02471493.
Vibrio vulnificus, a recently described strain of the halophilic Vibrio species, was isolated from the blood of a 73-year-old man, who developed rapidly progressive wound infection and fatal septicemia. Twenty-one patients with Vibrio vulnificus infection have been reported in the Japanese literature. Vibrio vulnificus most frequently causes primary septicemia and necrotising cellulitis after the eating of raw fish or shellfish or after exposure to seawater. The infection is characterized by its occurring during the warm months of the year, in patients with underlying diseases, especially liver diseases, and the mortality rate is surprisingly high. Clinicians should therefore consider the possibility of Vibrio vulnificus infection in the differential diagnosis of severe wound infections. Early surgical intervention and intensive antibiotic therapy are recommended for preventing the progress of the septicemia.
创伤弧菌是最近描述的一种嗜盐弧菌菌株，从一名73岁男性的血液中分离出来，该患者出现了快速进展的伤口感染和致命的败血症。日本文献中已报道了21例创伤弧菌感染患者。创伤弧菌最常引起原发性败血症和坏死性蜂窝织炎，通常发生在食用生鱼或贝类后或接触海水后。该感染的特点是在一年中的温暖月份发生，多见于患有基础疾病尤其是肝脏疾病的患者，死亡率出奇地高。因此，临床医生在对严重伤口感染进行鉴别诊断时应考虑创伤弧菌感染的可能性。建议早期进行手术干预和强化抗生素治疗，以防止败血症的进展。
