Trent J M
Ariz Med. 1981 Nov;38(11):836-9.
Recent technologic advances in human cancer genetics may provide valuable new tools in the diagnosis and prognosis of human cancer. Two new techniques, premature chromosome condensation (PCC), and the cloning of human tumor stem cells in agar, are described. It is suggested that as substantial progress occurs in our understanding of chromosome structure and function, additional clinically useful insights into the genetic basis and nature of cancer will be gained.
人类癌症遗传学领域最近的技术进步可能为人类癌症的诊断和预后提供有价值的新工具。本文描述了两种新技术,即早熟染色体凝集(PCC)和在琼脂中克隆人类肿瘤干细胞。有人认为,随着我们对染色体结构和功能的理解取得实质性进展,将获得对癌症的遗传基础和本质的更多临床上有用的见解。