Beard M E, Heaton D C, Hamer J W, Watson J, Fox H W, Crosier P S, Abbott G D
N Z Med J. 1981 Oct 14;94(693):249-52.
Five patients, three with severe aplasia and two with acute leukaemia have been treated by bone marrow transplantation (BMT). Four are alive and well with excellent graft function. One showed engraftment but died of acute graft-versus-host disease (GVH); this patient and his donor were hepatitis B antigen positive. Three show evidence of mild chronic GVH, two patients requiring control by immunosuppressive therapy. Bone marrow transplantation (BMT) has now become an established method of treatment in severe aplasia and in acute leukaemia and our results serve to emphasise this. The clinical and organisational problems associated with BMT are discussed.
5例患者接受了骨髓移植（BMT）治疗，其中3例为严重再生障碍性贫血，2例为急性白血病。4例存活且状况良好，移植功能极佳。1例出现植入，但死于急性移植物抗宿主病（GVHD）；该患者及其供者均为乙型肝炎抗原阳性。3例有轻度慢性GVHD的证据，2例患者需要通过免疫抑制治疗来控制。骨髓移植（BMT）现已成为严重再生障碍性贫血和急性白血病的一种既定治疗方法，我们的结果进一步证实了这一点。文中还讨论了与BMT相关的临床和组织问题。
