Simmer H H
J Clin Chem Clin Biochem. 1981 Jul;19(7):497-509.
Eugen Franz Freiherr von Gorup-Besanez, born 1817 in Graz, was appointed on 28. 11. 1846 to the post of lecturer in the faculty of medicine of the University of Erlangen. He had previously studied medicine in Vienna, Padua and Munich, followed by physiological and clinical-chemical studies under Louis Andreas Buchner in Munich, and further studies in organic and analytical chemistry under Friedrich Wöhler in Göttingen. In 1849 in Erlangen he became reader in organic and analytical chemistry, then, in 1855, moved to the faculty of philosophy as professor of chemistry. Von Gorup-Besanez was one of the early representatives of clinical chemistry in Germany. He tried to help clinicians by the analysis of urine, blood and tissues. In his lectures and through his books he was an outstanding teacher. His greatest contribution was the discovery of the amino acid valine. The lack of a laboratory in the medical faculty and his dissatisfaction with what could be achieved in clinical chemistry at that time may chiefly explain his move from the medical to the philosophical faculty. The life of von Gorup-Besanez illustrates the difficulties faced by clinical chemistry and its exponents in the middle of the 19th century.
欧根·弗朗茨·弗赖赫尔·冯·戈鲁普-贝萨内兹于1817年出生在格拉茨，1846年11月28日被任命为埃尔朗根大学医学院讲师。他此前在维也纳、帕多瓦和慕尼黑学习医学，之后在慕尼黑跟随路易·安德烈亚斯·布赫纳进行生理和临床化学研究，并在哥廷根跟随弗里德里希·维勒进一步学习有机化学和分析化学。1849年在埃尔朗根，他成为有机化学和分析化学的高级讲师，然后在1855年转到哲学院担任化学教授。冯·戈鲁普-贝萨内兹是德国临床化学的早期代表人物之一。他试图通过分析尿液、血液和组织来帮助临床医生。在他的讲座和著作中，他都是一位杰出的教师。他最大的贡献是发现了氨基酸缬氨酸。医学院缺乏实验室以及他对当时临床化学所能取得的成果的不满，可能主要解释了他从医学院转到哲学院的原因。冯·戈鲁普-贝萨内兹的一生说明了19世纪中叶临床化学及其从业者所面临的困难。
