Beretta G
Recent Results Cancer Res. 1982;80:259-63. doi: 10.1007/978-3-642-81685-7_41.
WHO clinical trial 6 studies the effect of long-term adjuvant therapy (chemotherapy, immunotherapy, and chemoimmunotherapy) after radical surgery in malignant melanoma with high risk of recurrence. The randomized study has been running for 67 months with 845 patients. This intermediate report seems to indicate that, concerning the relapse-free period, adjuvant treatment appears superior to surgery alone. However, no significant difference in the duration of survival is evident among the four treatment groups.
世界卫生组织临床试验6研究了根治性手术后长期辅助治疗（化疗、免疫治疗和化疗免疫治疗）对具有高复发风险的恶性黑色素瘤的疗效。这项随机研究已进行了67个月，涉及845名患者。这份中期报告似乎表明，就无复发生存期而言，辅助治疗似乎优于单纯手术。然而，四个治疗组之间在生存期方面没有明显差异。
