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阿替洛尔对心脏大小、心率及静息血压的影响(作者译)

[The effects of atenolol on the heart size, on the heart rate, and on the blood pressure at rest (author's transl)].

作者信息

Frisch P

出版信息

Med Klin. 1978 Oct 20;73(42):1477-80.

PMID:703677
Abstract

Cardiac functions like heart size, heart rate, and blood pressure were studied at rest in 23 digitalized and 24 not digitalized patinents recovering from a myocardial infarction, in 16 patients with arterial hypertension and in 9 patients with regulatory dysfunctions of the circulation before and after a three week period of treatment with 2 x 50 mg or 2 x 100 mg atenolol per day. The heart rate and the blood pressure of every patient were significantly reduced, whereas the heart size which was determined by X-ray in lying patient showed no clear difference. Furthermore, the determination of the heart size facilitates the decision of the additional digitalization when the start of a long-term treatment with beta-blocking agents seems to be necessary in the aforementioned patient groups.

摘要

对23例正在从心肌梗死中恢复的已洋地黄化患者和24例未洋地黄化患者、16例动脉高血压患者以及9例循环调节功能障碍患者在静息状态下的心脏功能(如心脏大小、心率和血压)进行了研究,这些患者每天接受2×50毫克或2×100毫克阿替洛尔治疗,为期三周,观察治疗前后的变化。每位患者的心率和血压均显著降低,而通过卧位患者X线测定的心脏大小无明显差异。此外,在上述患者群体中,当似乎有必要开始使用β受体阻滞剂进行长期治疗时,心脏大小的测定有助于决定是否需要额外进行洋地黄化。

相似文献

1
[The effects of atenolol on the heart size, on the heart rate, and on the blood pressure at rest (author's transl)].阿替洛尔对心脏大小、心率及静息血压的影响(作者译)
Med Klin. 1978 Oct 20;73(42):1477-80.
2
[Long term comparison between atenolol and a depot form of propranolol hydrochloride on the heart rate and blood pressure at rest and during physical work in normal subjects].[阿替洛尔与盐酸普萘洛尔长效剂型对正常受试者静息及体力活动时心率和血压的长期比较]
Arzneimittelforschung. 1980;30(8):1298-301.
3
[The effect of atenolol on contractility and hemodynamics of the infarcted heart in comparison to propranolol and practolol (author's transl)].与普萘洛尔和醋氨心安相比,阿替洛尔对梗死心脏收缩性和血流动力学的影响(作者译)
Arzneimittelforschung. 1975 Nov;25(11):1770-6.
4
[The hypertensive heart. VII. Effect of atenolol on the function, coronary haemodynamics and oxygen uptake of the left ventricle (author's transl)].
Dtsch Med Wochenschr. 1978 Nov 10;103(45):1785-9. doi: 10.1055/s-0028-1129343.
5
[Long term effects of the beta-adrenergic blocking agent atenolol (Tenormin) on coronary heart disease: a study of 125 patients (author's transl)].β-肾上腺素能阻滞剂阿替洛尔(氨酰心安)对冠心病的长期影响:125例患者的研究(作者译)
Med Klin. 1978 Jan 20;73(3):101-5.
6
Comparison of antihypertensive activity of atenolol and methyldopa at rest and during exercise.阿替洛尔和甲基多巴在静息及运动状态下的降压活性比较。
Int J Clin Pharmacol Ther Toxicol. 1981 Oct;19(10):440-4.
7
Ambulatory blood pressure and heart rate during once-daily, randomized, crossover administration of carteolol and atenolol.在单次每日随机交叉给予卡替洛尔和阿替洛尔期间的动态血压和心率。
Clin Ther. 1994 Mar-Apr;16(2):181-90.
8
[Effects of a new cardioselective beta-adrenergic blocker (atenolol) on airway resistance in chronic obstructive disease (author's transl)].
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9
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10
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Clin Pharmacol Ther. 1998 Nov;64(5):522-35. doi: 10.1016/S0009-9236(98)90135-7.