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阿替洛尔对心脏大小、心率及静息血压的影响(作者译)

[The effects of atenolol on the heart size, on the heart rate, and on the blood pressure at rest (author's transl)].

作者信息

Frisch P

出版信息

Med Klin. 1978 Oct 20;73(42):1477-80.

PMID:703677
Abstract

Cardiac functions like heart size, heart rate, and blood pressure were studied at rest in 23 digitalized and 24 not digitalized patinents recovering from a myocardial infarction, in 16 patients with arterial hypertension and in 9 patients with regulatory dysfunctions of the circulation before and after a three week period of treatment with 2 x 50 mg or 2 x 100 mg atenolol per day. The heart rate and the blood pressure of every patient were significantly reduced, whereas the heart size which was determined by X-ray in lying patient showed no clear difference. Furthermore, the determination of the heart size facilitates the decision of the additional digitalization when the start of a long-term treatment with beta-blocking agents seems to be necessary in the aforementioned patient groups.

摘要

对23例正在从心肌梗死中恢复的已洋地黄化患者和24例未洋地黄化患者、16例动脉高血压患者以及9例循环调节功能障碍患者在静息状态下的心脏功能(如心脏大小、心率和血压)进行了研究,这些患者每天接受2×50毫克或2×100毫克阿替洛尔治疗,为期三周,观察治疗前后的变化。每位患者的心率和血压均显著降低,而通过卧位患者X线测定的心脏大小无明显差异。此外,在上述患者群体中,当似乎有必要开始使用β受体阻滞剂进行长期治疗时,心脏大小的测定有助于决定是否需要额外进行洋地黄化。

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