Ward L C, Boorman K N, Buttery P J
Horm Metab Res. 1982 Jan;14(1):30-3. doi: 10.1055/s-2007-1018913.
The uptake of amino acids by the perfused rat hind-limb at increasing perfusate amino acid concentrations was studied both in the presence and absence of insulin. The uptake of the essential amino acids could be correlated with their concentrations in muscle protein. A net protein synthetic rate was calculated from the predicted incorporation of phenylalanine and was 33 nmol h-1g-1, a value in good agreement with those obtained in other studies. The possible significance of the supply of leucine in the regulation of muscle protein synthesis is considered.
在有胰岛素和无胰岛素的情况下，研究了灌注液中氨基酸浓度增加时大鼠后肢对氨基酸的摄取情况。必需氨基酸的摄取量与其在肌肉蛋白质中的浓度相关。根据苯丙氨酸的预测掺入量计算出净蛋白质合成速率为33 nmol h-1g-1，该值与其他研究获得的值高度一致。研究了亮氨酸供应在调节肌肉蛋白质合成中的可能意义。
