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[乙酰胆碱和血清素局部离子电渗疗法对兔颈上神经节神经元的影响]

[Effect of local iontophoretic application of acetylcholine and serotonin on rabbit superior cervical ganglion neurons].

作者信息

Skok V I, Selianko A A

出版信息

Neirofiziologiia. 1978;10(5):519-24.

PMID:703904
Abstract

The effect of iontophoretically applied acetylcholine and serotonin (5-hydroxytryptamine) on the neurons of the rabbit isolated superior cervical ganglion was studied by means of intracellular recording. It is found that the ganglion cell soma has only nicotinic receptors and no muscarinic receptors; nicotinic receptors are dispersed nonuniformly on the surface of the soma membrane. Spontaneous EPSPs were observed due to ACh application, which indicates excitation of presynaptic terminals. In about a half of ganglion neurons the soma possessed serotonin receptors.

摘要

通过细胞内记录法研究了离子电渗法施加乙酰胆碱和血清素(5-羟色胺)对兔离体颈上神经节神经元的影响。发现神经节细胞体仅具有烟碱受体,而没有毒蕈碱受体;烟碱受体在细胞体膜表面分布不均匀。施加乙酰胆碱后观察到自发兴奋性突触后电位(EPSP),这表明突触前终末受到了兴奋。在大约一半的神经节神经元中,细胞体具有血清素受体。

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