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Production and evaluation of antibody to the heat-stable enterotoxin from a human strain of enterotoxigenic Escherichia coli.人源产肠毒素大肠杆菌热稳定肠毒素抗体的制备与评估
Appl Environ Microbiol. 1981 Oct;42(4):611-4. doi: 10.1128/aem.42.4.611-614.1981.
2
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Simple and reliable enzyme-linked immunosorbent assay with monoclonal antibodies for detection of Escherichia coli heat-stable enterotoxins.用单克隆抗体检测大肠杆菌热稳定肠毒素的简单可靠的酶联免疫吸附测定法。
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Physiochemical properties of a heat-stable enterotoxin produced by Escherichia coli of human origin.源自人类的大肠杆菌产生的一种热稳定肠毒素的理化特性。
Infect Immun. 1980 Jun;28(3):1051-3. doi: 10.1128/iai.28.3.1051-1053.1980.
2
Escherichia coli heat-stable enterotoxin: rapid method of purification and some characteristics of the toxin.大肠杆菌热稳定肠毒素：纯化的快速方法及该毒素的一些特性
Infect Immun. 1980 May;28(2):469-74. doi: 10.1128/iai.28.2.469-474.1980.
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Purification and characterization of heat-stable enterotoxin produced by a strain of E. coli pathogenic for man.一株对人类致病的大肠杆菌产生的热稳定肠毒素的纯化与特性分析
J Biol Chem. 1980 May 25;255(10):4716-21.
4
Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu.利用幼鼠检测大肠杆菌肠毒素：在檀香山儿童腹泻研究中的应用
J Infect Dis. 1972 Apr;125(4):407-11. doi: 10.1093/infdis/125.4.407.
5
Stability of 125I-labeled staphylococcal enterotoxins in solid-phase radioimmunoassay.125I标记的葡萄球菌肠毒素在固相放射免疫分析中的稳定性
Appl Microbiol. 1975 Jun;29(6):776-9. doi: 10.1128/am.29.6.776-779.1975.
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Purification and partial characterization of heat-stable enterotoxin of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌热稳定肠毒素的纯化及部分特性研究
Infect Immun. 1979 Sep;25(3):978-85. doi: 10.1128/iai.25.3.978-985.1979.
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Evidence for two heat-stable enterotoxins produced by enterotoxigenic Escherichia coli.产肠毒素大肠杆菌产生两种热稳定肠毒素的证据。
Infect Immun. 1979 Jun;24(3):965-6. doi: 10.1128/iai.24.3.965-966.1979.
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Purification and chemical characterization of the heat-stable enterotoxin produced by porcine strains of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌猪菌株产生的热稳定肠毒素的纯化及化学特性分析
Infect Immun. 1978 Mar;19(3):1021-30. doi: 10.1128/iai.19.3.1021-1030.1978.

人源产肠毒素大肠杆菌热稳定肠毒素抗体的制备与评估

Production and evaluation of antibody to the heat-stable enterotoxin from a human strain of enterotoxigenic Escherichia coli.

作者信息

Kauffman P E

出版信息

Appl Environ Microbiol. 1981 Oct;42(4):611-4. doi: 10.1128/aem.42.4.611-614.1981.

DOI:10.1128/aem.42.4.611-614.1981
PMID:7039508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC244070/
Abstract

Escherichia coli heat-stable enterotoxin was coupled to bovine serum albumin by a carbodiimide reagent. Antibody to the conjugate was produced by immunization of rabbits. Data from radioimmunoassay and infant mouse tests indicate the presence of antibody to the enterotoxin. The antisera can be used in a radioimmunoassay to measure enterotoxin in various fluids.

摘要

用碳二亚胺试剂将大肠杆菌热稳定肠毒素与牛血清白蛋白偶联。通过免疫兔子产生针对该偶联物的抗体。放射免疫测定和幼鼠试验的数据表明存在针对肠毒素的抗体。该抗血清可用于放射免疫测定以测量各种体液中的肠毒素。