人源产肠毒素大肠杆菌热稳定肠毒素抗体的制备与评估
Production and evaluation of antibody to the heat-stable enterotoxin from a human strain of enterotoxigenic Escherichia coli.
作者信息
Kauffman P E
出版信息
Appl Environ Microbiol. 1981 Oct;42(4):611-4. doi: 10.1128/aem.42.4.611-614.1981.
Abstract
Escherichia coli heat-stable enterotoxin was coupled to bovine serum albumin by a carbodiimide reagent. Antibody to the conjugate was produced by immunization of rabbits. Data from radioimmunoassay and infant mouse tests indicate the presence of antibody to the enterotoxin. The antisera can be used in a radioimmunoassay to measure enterotoxin in various fluids.
摘要
用碳二亚胺试剂将大肠杆菌热稳定肠毒素与牛血清白蛋白偶联。通过免疫兔子产生针对该偶联物的抗体。放射免疫测定和幼鼠试验的数据表明存在针对肠毒素的抗体。该抗血清可用于放射免疫测定以测量各种体液中的肠毒素。
相似文献
1
Production and evaluation of antibody to the heat-stable enterotoxin from a human strain of enterotoxigenic Escherichia coli.人源产肠毒素大肠杆菌热稳定肠毒素抗体的制备与评估
Appl Environ Microbiol. 1981 Oct;42(4):611-4. doi: 10.1128/aem.42.4.611-614.1981.
2
Immunological properties of porcine enterotoxigenic Escherichia coli heat-stable (ST) enterotoxins.猪产肠毒素大肠杆菌热稳定（ST）肠毒素的免疫学特性
Comp Immunol Microbiol Infect Dis. 1984;7(3-4):157-64. doi: 10.1016/0147-9571(84)90021-3.
3
Immunological properties of Escherichia coli heat-stable enterotoxins: development of a radioimmunoassay specific for heat-stable enterotoxins with suckling mouse activity.大肠杆菌热稳定肠毒素的免疫学特性：针对具有乳鼠活性的热稳定肠毒素的放射免疫测定法的开发。
Infect Immun. 1981 Jul;33(1):193-8. doi: 10.1128/iai.33.1.193-198.1981.
4
Generation of high-titer of neutralizing polyclonal antibodies against heat-stable enterotoxin (STa) of enterotoxigenic Escherichia coli.针对肠产毒性大肠杆菌热稳定肠毒素（STa）产生高滴度中和多克隆抗体。
Vaccine. 2012 Oct 5;30(45):6341-6. doi: 10.1016/j.vaccine.2012.06.064. Epub 2012 Jul 2.
5
Production of neutralizing monoclonal antibodies to Escherichia coli heat-stable enterotoxin.抗大肠杆菌热稳定肠毒素中和单克隆抗体的制备
Infect Immun. 1985 Jan;47(1):242-6. doi: 10.1128/iai.47.1.242-246.1985.
6
Immunization of swine with heat-stable Escherichia coli enterotoxin coupled to a carrier protein does not protect suckling pigs against an Escherichia coli strain that produces heat-stable enterotoxin.用与载体蛋白偶联的热稳定大肠杆菌肠毒素对猪进行免疫接种，并不能保护哺乳仔猪抵御产生热稳定肠毒素的大肠杆菌菌株。
Infect Immun. 1983 Feb;39(2):990-2. doi: 10.1128/iai.39.2.990-992.1983.
7
Development of a competitive enzyme-linked immunosorbent assay (ELISA) for Escherichia coli heat-stable enterotoxin (STa).用于检测大肠杆菌热稳定肠毒素（STa）的竞争性酶联免疫吸附测定（ELISA）的开发。
J Immunol Methods. 1984 Dec 31;75(2):295-307. doi: 10.1016/0022-1759(84)90113-3.
8
9
Reactivity of human serum antibody with lipopolysaccharide O 78 antigen from enterotoxigenic Escherichia coli.人血清抗体与产肠毒素大肠杆菌脂多糖O 78抗原的反应性。
Epidemiol Infect. 1992 Apr;108(2):315-22. doi: 10.1017/s0950268800049785.
10
Detection of antibody to E. coli heat-labile enterotoxin in bovine sera samples from various regions of France.法国不同地区牛血清样本中大肠杆菌不耐热肠毒素抗体的检测。
Zentralbl Veterinarmed B. 1981;28(4):341-3. doi: 10.1111/j.1439-0450.1981.tb01921.x.
引用本文的文献
1
Coupling enterotoxigenic Escherichia coli heat-stable peptide toxin with 8-arm PEG enhances immunogenicity.将肠产毒性大肠埃希菌耐热肠毒素肽与 8 臂聚乙二醇偶联可增强其免疫原性。
J Pept Sci. 2025 Jan;31(1):e3647. doi: 10.1002/psc.3647. Epub 2024 Aug 1.
2
Development of an enterotoxigenic vaccine based on the heat-stable toxin.基于耐热毒素的肠毒素疫苗的研制。
Hum Vaccin Immunother. 2019;15(6):1379-1388. doi: 10.1080/21645515.2018.1496768. Epub 2018 Aug 21.
3
Genetic fusions of heat-labile toxoid (LT) and heat-stable toxin b (STb) of porcine enterotoxigenic Escherichia coli elicit protective anti-LT and anti-STb antibodies.猪产肠毒素大肠杆菌的热不稳定类毒素（LT）和热稳定毒素b（STb）的基因融合物可引发具有保护作用的抗LT和抗STb抗体。
Clin Vaccine Immunol. 2010 Aug;17(8):1223-31. doi: 10.1128/CVI.00095-10. Epub 2010 May 26.
4
Heat-stable enterotoxin of enterotoxigenic Escherichia coli as a vaccine target.肠产毒性大肠杆菌热稳定肠毒素作为疫苗靶标。
Infect Immun. 2010 May;78(5):1824-31. doi: 10.1128/IAI.01397-09. Epub 2010 Mar 15.
5
Development of a vaccine of cross-linked heat-stable and heat-labile enterotoxins that protects against Escherichia coli producing either enterotoxin.一种由交联的热稳定和热不稳定肠毒素组成的疫苗的研发，该疫苗可预防产生任一肠毒素的大肠杆菌。
Infect Immun. 1982 Aug;37(2):550-7. doi: 10.1128/iai.37.2.550-557.1982.
6
Simple and reliable enzyme-linked immunosorbent assay with monoclonal antibodies for detection of Escherichia coli heat-stable enterotoxins.用单克隆抗体检测大肠杆菌热稳定肠毒素的简单可靠的酶联免疫吸附测定法。
J Clin Microbiol. 1984 Jul;20(1):59-64. doi: 10.1128/jcm.20.1.59-64.1984.
7
Properties of synthetically produced Escherichia coli heat-stable enterotoxin.合成产生的大肠杆菌热稳定肠毒素的特性。
Infect Immun. 1983 Jan;39(1):117-21. doi: 10.1128/iai.39.1.117-121.1983.
8
Escherichia coli diarrhoea.大肠杆菌性腹泻
J Hyg (Lond). 1985 Dec;95(3):531-50. doi: 10.1017/s0022172400060666.
本文引用的文献
1
Physiochemical properties of a heat-stable enterotoxin produced by Escherichia coli of human origin.源自人类的大肠杆菌产生的一种热稳定肠毒素的理化特性。
Infect Immun. 1980 Jun;28(3):1051-3. doi: 10.1128/iai.28.3.1051-1053.1980.
2
Escherichia coli heat-stable enterotoxin: rapid method of purification and some characteristics of the toxin.大肠杆菌热稳定肠毒素：纯化的快速方法及该毒素的一些特性
Infect Immun. 1980 May;28(2):469-74. doi: 10.1128/iai.28.2.469-474.1980.
3
Purification and characterization of heat-stable enterotoxin produced by a strain of E. coli pathogenic for man.一株对人类致病的大肠杆菌产生的热稳定肠毒素的纯化与特性分析
J Biol Chem. 1980 May 25;255(10):4716-21.
4
Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu.利用幼鼠检测大肠杆菌肠毒素：在檀香山儿童腹泻研究中的应用
J Infect Dis. 1972 Apr;125(4):407-11. doi: 10.1093/infdis/125.4.407.
5
Stability of 125I-labeled staphylococcal enterotoxins in solid-phase radioimmunoassay.125I标记的葡萄球菌肠毒素在固相放射免疫分析中的稳定性
Appl Microbiol. 1975 Jun;29(6):776-9. doi: 10.1128/am.29.6.776-779.1975.
6
Purification and partial characterization of heat-stable enterotoxin of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌热稳定肠毒素的纯化及部分特性研究
Infect Immun. 1979 Sep;25(3):978-85. doi: 10.1128/iai.25.3.978-985.1979.
7
Evidence for two heat-stable enterotoxins produced by enterotoxigenic Escherichia coli.产肠毒素大肠杆菌产生两种热稳定肠毒素的证据。
Infect Immun. 1979 Jun;24(3):965-6. doi: 10.1128/iai.24.3.965-966.1979.
8
Purification and chemical characterization of the heat-stable enterotoxin produced by porcine strains of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌猪菌株产生的热稳定肠毒素的纯化及化学特性分析
Infect Immun. 1978 Mar;19(3):1021-30. doi: 10.1128/iai.19.3.1021-1030.1978.
Zotero 插件