Ellis R J
Biochem Soc Symp. 1981(46):223-34.
A characteristic feature of all cells is the transport of proteins across membranes. Biochemical studies with isolated subcellular components have revealed two types of proteins transport: co-translational, in which transport and synthesis are simultaneous, and post-translational, where transport occurs after the protein has been released form the ribosomes. Both types of transport involve interactions between particular regions of the protein and the membrane to be traversed. The details of this interaction are obscure. This review introduces the subject with emphasis on genetic studies with bacteria and biochemical studies with isolated chloroplasts.
所有细胞的一个特征是蛋白质跨膜运输。对分离出的亚细胞成分进行的生化研究揭示了两种蛋白质运输类型：共翻译运输，即运输和合成同时进行；以及翻译后运输，即蛋白质从核糖体释放后才发生运输。这两种运输类型都涉及蛋白质特定区域与要穿越的膜之间的相互作用。这种相互作用的细节尚不清楚。本综述介绍了这一主题，重点是对细菌的遗传学研究和对分离叶绿体的生化研究。
