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滋养层疾病患者中,人绒毛膜促性腺激素的放射受体分析与放射免疫分析的对比研究。

A comparative study between radioreceptor assay and radioimmunoassay for hCG in patients with trophoblastic disease.

作者信息

Kletzky O A, Scott J Z, Morrow C P, Mishell D R

出版信息

Obstet Gynecol. 1978 Sep;52(3):328-31.

PMID:703989
Abstract

The results of a urinary quantitative radioreceptor assay (RRA) were compared with those obtained with an established specific radioimmunoassay (RIA) for hCG in a group of patients with trophoblastic disease. A good correlation (r = 0.95) was found between the two methods for values greater than 10 mIU/ml of hCG. A specific RIA for hCG should be used when the hCG levels fall below 10 mIU/ml. With the use of this urinary RRA, the clinician can follow patients with hydatidiform more for up to 10 weeks after evacuation and have the hCG titer available on the same day the specimen is obtained.

摘要

在一组滋养细胞疾病患者中,将尿定量放射受体分析(RRA)的结果与用已确立的人绒毛膜促性腺激素(hCG)特异性放射免疫分析(RIA)所获得的结果进行了比较。对于hCG值大于10 mIU/ml的情况,两种方法之间发现有良好的相关性(r = 0.95)。当hCG水平低于10 mIU/ml时,应使用hCG特异性RIA。通过使用这种尿RRA,临床医生在清宫后长达10周的时间里可以对葡萄胎患者进行随访,并在获取标本的同一天得到hCG滴度结果。

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