硫酸特布他林对儿童运动诱发性哮喘的影响。

The effect of terbutaline sulphate on exercise-induced asthma in children.

作者信息

Weinberg E G

出版信息

S Afr Med J. 1982 Apr 17;61(16):587-9.

Abstract

Terbutaline sulphate (Bricanyl; Keatings) aerosol or placebo aerosol was administered in a randomized fashion to 26 asthmatic children with proven exercise-induced asthma. The children were then subjected to the modified standard exercise challenge test involving running on the level for 6 minutes. Terbutaline sulphate aerosol had a marked protective effect against exercise-induced asthma in these children. Compared with placebo, a significant reduction in exercise-induced bronchospasm was achieved. The improved design of the mouthpiece, incorporating a newly introduced 'misting tube' enabled the children to handle the apparatus easily. The need to synchronize the activation of the aerosol with inhalation was eliminated. Terbutaline aerosol can be recommended to protect children affected by exercise-induced asthma. The preparation can be given prior to the exercise challenge and will offer prolonged and adequate protection against exercise asthma.

摘要

硫酸特布他林（博利康尼；基廷斯）气雾剂或安慰剂气雾剂以随机方式给予26名已证实患有运动诱发性哮喘的哮喘儿童。然后让这些儿童进行改良的标准运动激发试验，包括在平地上跑步6分钟。硫酸特布他林气雾剂对这些儿童的运动诱发性哮喘有显著的保护作用。与安慰剂相比，运动诱发的支气管痉挛明显减轻。口含器设计的改进，包括新引入的“喷雾管”，使儿童能够轻松操作该装置。消除了气雾剂激活与吸入同步的需要。硫酸特布他林气雾剂可推荐用于保护受运动诱发性哮喘影响的儿童。该制剂可在运动激发试验前给予，并将为运动性哮喘提供持久而充分的保护。