Santucci A, Aguglia F, Violi F, De Mattia G
Am J Cardiol. 1982 Apr 21;49(6):1513-4. doi: 10.1016/0002-9149(82)90372-1.
The effect of captopril on intralymphocytic sodium concentration in hypertensive subjects was studied. After acute and chronic treatment the intralymphocytic sodium content decreased. The possibility is discussed that a similar decrease might also occur in smooth muscle cells, thus enhancing the hypotensive effect of captopril.
研究了卡托普利对高血压患者淋巴细胞内钠浓度的影响。急性和慢性治疗后,淋巴细胞内钠含量降低。文中讨论了平滑肌细胞中可能也会出现类似降低的情况,从而增强卡托普利的降压效果。