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法洛四联症的根治性手术矫正:手术治疗后异丙肾上腺素在间歇正压通气和自主通气中的效果比较(作者译)

[Radical surgical correction of tetralogy of Fallot: comparison between the effects of isoproterenol in IPPV and spontaneous-ventilation after surgical treatment (author's transl)].

作者信息

Clementi G, Memè M, Burchiani M, Coletta R, Di Tizio S, Punzo S, Pisani E

出版信息

G Ital Cardiol. 1981;11(10):1472-6.

PMID:7042437
Abstract

The AA. studied 7 patients affected by Tetralogy of Fallot; their ages were between 4 and 20 years. At the end of the radical surgical correction we studied their haemodynamics. From the analysis of the data we found that using beta-agonist drugs (Isuprel 0.05 mcg x Kg x min) there were no change in the haemodynamic data when the patients were kept under positive pressure ventilation. In spontaneous ventilation we observed that the same data can raise the cardiac index of 22%, lower the total peripheral resistances (20%) and the pulmonary vascular resistances (8%) and the intrapulmonary shunt (8%).

摘要

研究人员对7名患有法洛四联症的患者进行了研究;他们的年龄在4至20岁之间。在根治性手术矫正结束时,研究人员对他们的血液动力学进行了研究。通过数据分析发现,使用β - 激动剂药物(异丙肾上腺素0.05微克/千克/分钟)时,当患者处于正压通气状态下,血液动力学数据没有变化。在自主通气时,研究人员观察到相同的数据可使心脏指数提高22%,降低总外周阻力(20%)、肺血管阻力(8%)和肺内分流(8%)。

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