Economidou J
Paediatrician. 1982;11(3-4):157-77.
New developments in the symptomatic treatment of beta-thalassaemia major are expected to improve the quality of life and survival of the patients. However, there are still many problems related to the clinical management of the patients due to the severity of the disease per se and the complications of blood transfusion and iron overload. Some of the problems related to the treatment of hypersplenism, post-transfusion complications, bone manifestations, hormonal deficiencies and haemosiderosis are reviewed in the light of recent investigations.
重型β地中海贫血对症治疗的新进展有望改善患者的生活质量和生存率。然而，由于疾病本身的严重性以及输血和铁过载的并发症，患者的临床管理仍存在许多问题。本文根据最近的研究，对与脾功能亢进治疗、输血后并发症、骨骼表现、激素缺乏和血色素沉着症相关的一些问题进行了综述。
