Davidenkova E F
Zh Nevropatol Psikhiatr Im S S Korsakova. 1982;82(3):9-17.
The author demonstrates the development of S. N. Davidenkov's concepts concerning the problem of treating and preventing hereditary diseases in modern genetics. The results of research work carried out by the author and her colleagues are presented. A new direction in the treatment of hereditary diseases, that is, targeted delivery of microincapsulated macromolecules (enzymes) to the cells, as an alternative to enzymotherapy, is described, and the results attained in this field are presented. Prospects of the new direction are demonstrated. Problems of prophylaxis and, particularly, prenatal diagnosis of hereditary diseases are described.
作者阐述了S. N. 达维坚科夫关于现代遗传学中遗传性疾病治疗和预防问题的概念发展。介绍了作者及其同事开展的研究工作成果。描述了遗传性疾病治疗的一个新方向，即作为酶疗法的替代方法，将微囊化大分子（酶）靶向递送至细胞，并展示了该领域取得的成果。展示了这一新方向的前景。描述了遗传性疾病的预防问题，尤其是产前诊断问题。
