乙醇脱氢酶的合成抑制剂。4-位含有不饱和烃残基的吡唑类化合物。
Synthetic inhibitors of alcohol dehydrogenase. Pyrazoles containing an unsaturated hydrocarbon residue in the 4-position.
作者信息
Tolf B R, Dahlbom R, Theorell H, Akeson A
出版信息
Acta Chem Scand B. 1982;36(2):101-7. doi: 10.3891/acta.chem.scand.36b-0101.
Abstract
A series of pyrazoles containing an unsaturated hydrocarbon residue in the 4-position has been synthesized and tested for ability to inhibit the activity of the enzyme liver alcohol dehydrogenase. These compounds were found to be less active than the corresponding saturated analogues.
摘要
一系列在4位含有不饱和烃残基的吡唑已被合成，并测试了其抑制肝脏乙醇脱氢酶活性的能力。发现这些化合物的活性低于相应的饱和类似物。
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