Vogl S E, Berenzweig M, Camacho F, Greenwald E, Kaplan B H
Cancer. 1982 Jul 1;50(1):24-6. doi: 10.1002/1097-0142(19820701)50:1<24::aid-cncr2820500106>3.0.co;2-r.
Thirty patients with advanced non-small cell bronchogenic carcinoma were treated with cis-platin, 75 mg/M2 weekly for three weeks, then every three weeks. Eighteen were ambulatory, 22 had distant metastases, 14 had prior irradiation, and none had prior chemotherapy. Ten patients (33%) had objective remissions lasting a median of three months. Responders lived a median of five months, compared to three months for nonresponders. Transient mild azotemia was noted in twelve patients. Cis-platin has definite but modest activity in non-small cell bronchogenic carcinoma.
30例晚期非小细胞支气管源性癌患者接受顺铂治疗，剂量为75mg/M2，每周一次，共三周，之后每三周一次。18例患者可自由活动，22例有远处转移，14例曾接受过放疗，且均未接受过化疗。10例患者（33%）出现客观缓解，缓解期中位数为三个月。缓解者的生存期中位数为五个月，未缓解者为三个月。12例患者出现短暂性轻度氮质血症。顺铂在非小细胞支气管源性癌中具有一定但适度的活性。
