用于测量实验动物体感功能障碍的心理物理学方法。
Psychophysical methods for the measurement of somatosensory dysfunction of laboratory animals.
作者信息
Cabe P A
出版信息
Environ Health Perspect. 1982 Apr;44:93-100. doi: 10.1289/ehp.824493.
Abstract
Somatosensory dysfunction is a widely reported clinical consequence of chemical exposure. Assessment of such dysfunction should be an important component of agent safety testing, necessarily implying evaluation of psychophysical functions in laboratory animals. The logic of testing agent-induced sensory dysfunction, conceptual and practical factors affecting such tests, and the categories of experimental methods available are reviewed.
摘要
体感功能障碍是化学物质暴露后广泛报道的临床后果。对此类功能障碍的评估应是药剂安全性测试的重要组成部分，这必然意味着要对实验动物的心理物理功能进行评估。本文综述了测试药剂诱导的感觉功能障碍的逻辑、影响此类测试的概念和实际因素，以及可用的实验方法类别。
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